Wednesday, April 10, 2013

Student arrested in Texas college stabbing attack

Students run from the Lone Star College's Cy-Fair campus in Cypress, Texas, where a student went on a building-to-building stabbing attack Tuesday, April 9, 2013. The attacker wounded at least 14 people before being subdued and arrested, authorities said. (AP Photo/Houston Chronicle, James Nielsen) MANDATORY CREDIT

Students run from the Lone Star College's Cy-Fair campus in Cypress, Texas, where a student went on a building-to-building stabbing attack Tuesday, April 9, 2013. The attacker wounded at least 14 people before being subdued and arrested, authorities said. (AP Photo/Houston Chronicle, James Nielsen) MANDATORY CREDIT

Students run from the Lone Star College's Cy-Fair campus in Cypress, Texas, where a student went on a building-to-building stabbing attack Tuesday, April 9, 2013. The attacker wounded at least 14 people before being subdued and arrested, authorities said. (AP Photo/Houston Chronicle, James Nielsen) MANDATORY CREDIT

A Texas State Trooper stands at an entrance as vehicles leave from the Cy-Fair campus of Lone Star Community College in Cypress, Texas on Tuesday, April 9, 2013. More than a dozen people were wounded when a suspect went building-to-building in an apparent stabbing attack at the college campus authorities said. The attack on the Lone Star Community College System's campus in Cypress sent at least 12 people to area hospitals, including four people taken by helicopter, according to Cy-Fair Volunteer Fire Department spokesman Robert Rasa. (AP Photo/Houston Chronicle, Melissa Phillip) MANDATORY CREDIT

A police helicopter circles above the Cy-Fair campus of Lone Star Community College in Cypress, Texas, where officials say about a dozen people have been wounded in a stabbing attack Tuesday, April 9, 2013. The Harris County Sheriff's department confirmed at least 11 people wounded and that authorities have one suspect in custody. (AP Photo/Houston Chronicle, Melissa Phillip)

Cassie Foe hugs classmate Christian Wilson after leaving from the Cy-Fair campus of Lone Star Community College in Cypress, Texas, where she witnessed a male getting stabbed on Tuesday, April 9, 2013. More than a dozen people were wounded when a suspect went building-to-building in an apparent stabbing attack at the college campus authorities said. The attack on the Lone Star Community College System's campus in Cypress sent at least 12 people to area hospitals, including four people taken by helicopter, according to Cy-Fair Volunteer Fire Department spokesman Robert Rasa. (AP Photo/Houston Chronicle, Melissa Phillip) MANDATORY CREDIT

CYPRESS, Texas (AP) ? A student went on a building-to-building stabbing attack at a Texas community college Tuesday, wounding at least 14 people before being subdued and arrested, authorities said.

The attack about 11:20 a.m. on the Lone Star Community College System's campus in Cypress sent at least 12 people to area hospitals, including four taken by helicopter, according to Cy-Fair Volunteer Fire Department spokesman Robert Rasa. He said several people refused treatment at the scene.

Harris County Sheriff Adrian Garcia said officers responded to the campus after receiving a call about a male "on the loose" stabbing people. He said it was not immediately clear what type of weapon was used.

"Some of the details in the call slip did indicate that students or faculty were actively responding to work to subdue this individual," Garcia said, describing the man as being about 21 years old and enrolled at the college. "So we're proud of those folks, but we're glad no one else is injured any more severely than they are."

Student Michael Chalfan said he was walking to class when he saw a group of police officers running after the suspect. He said one of the officers used a stun gun to help subdue the man, who Chalfan said he recognized from a drama class last year.

Chalfan described the man as "eccentric," saying he often wore gloves and was known to carry stuffed animals. He said although the man was teased by fellow students, he remained friendly.

"I'm surprised because he didn't look like he was hateful to the world," Chalfan said.

Lone Star officials initially urged people on campus, about 25 miles northwest of downtown Houston, to take shelter and be on alert for a second suspect. But the sheriff's department said authorities believe just one person was responsible.

"It was the same suspect going from building to building," department spokesman Thomas Gilliland said.

Michelle Alvarez told the Houston Chronicle she saw the attacker running toward other students and tried to back out of the way. She said she didn't even feel it as he swiped at her neck.

"He came running and swinging at my neck, as I tried to get out of the way," she said.

Garcia said buildings still were being searched Tuesday afternoon. Long lines of vehicles carrying students and staff streamed off campus as law enforcement directed traffic away from the school.

Student Teaundrae Perryman said he was in class when he received a text message from a friend and went outside to see a young woman being loaded into an ambulance with what appeared to be stab wounds to either her neck or head. He said he didn't receive an email alert from the college until 11:56 a.m.

"I was concerned but I wasn't afraid because I was with a large group of people," the 21-year-old said, later adding, "The police got to the scene very quickly."

The four people taken by helicopter and two others with moderate injuries were taken to Memorial Hermann Hospital. Of those six, two patients remained in critical condition, three have been upgraded to good condition and one was discharged Tuesday afternoon, hospital spokeswoman Alex Rodriguez said.

One student said she learned one of her classmates was stabbed after leaving the school's Health Science Center building.

"I called to check on another classmate who was still inside the building and she said the classroom was on lockdown and she said one of the classmates had been stabbed," said Margo Shimfarr-Evans told KHOU-TV. "It happened in the hallway."

Courtland Sedlachek, 18, was in class when his phone started buzzing along with the phones of everyone else in class. The room was temporarily locked down, but students were let out and off campus a short time later, in what Sedlachek described as an orderly evacuation.

He described his reaction as a "little bit of nervousness."

The attack came three months after a different Lone Star campus was the site of a shooting in which two people were hurt. The suspected gunman in that incident is charged with aggravated assault.

___

Associated Press writer Nomaan Merchant in Dallas contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-04-09-Texas%20College-Stabbing/id-2ca5cfdfa1c24a06ac51182492c2c87f

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Tuesday, April 9, 2013

Showdown vote on gun reforms set for Senate

WASHINGTON (AP) ? Senate Democrats set Congress' first showdown vote on new gun restrictions for Thursday as a small but growing number of Republicans appeared willing to join them in opposing conservatives' efforts to block debate from even starting.

Making it personal, relatives of victims of the Connecticut school shootings lobbied senators face-to-face at the Capitol on Tuesday in hopes of persuading enough Republicans to back a debate and votes on meaningful gun restrictions.

Majority Leader Harry Reid, D-Nev., told reporters Tuesday that he does not know if Democrats will get the 60 votes needed to break an effort by conservatives to prevent consideration of the legislation. But at least six Republicans have indicated an openness to begin debate. There are 53 Democrats and two independents who generally vote with them in the 100-member Senate, but some moderate Democratic senators might defect on an issue that provokes strong emotions among their constituents.

"It would be a real slap in the face to the American people not to do something on background checks, on school safety, on federal trafficking which everybody thinks is a good idea," Reid said, mentioning the elements of the Democratic firearms measure.

A Senate vote to begin debating the legislation would be a temporary victory for President Barack Obama's gun-control drive. It remains unclear, though, whether there are enough votes for final approval of the legislation.

Obama was calling senators from both parties Tuesday to push for the gun bill, according to a White House official.

Before meeting privately with senators at the Capitol, the Connecticut families had breakfast with Vice President Joe Biden at his residence at the Naval Observatory, according to an administration official. That official spoke only on condition of anonymity because the official was not authorized to speak publicly about the meeting.

Obama's gun-control proposals have hit opposition from the National Rifle Association and are struggling in Congress, nearly four months after the issue was catapulted into the national arena by December's slaying of 20 first-graders and six educators in Newtown, Conn.

In a letter to Reid on Monday, 13 conservatives said they will use procedural tactics to try preventing the Senate from considering firearms restrictions, headlined by background checks for more gun buyers and bans on assault weapons and high-capacity ammunition magazines.

Senate Minority Leader Mitch McConnell, R-Ky., said Monday that he would join the conservatives in trying to block debate.

Earlier Tuesday, Reid stood on the Senate floor before a poster-sized photo of a white picket fence with 26 slats, each bearing the name of a Newtown victim.

"We have a responsibility to safeguard these little kids," said Reid, D-Nev. "And unless we do something more than what's the law today, we have failed."

In a hopeful sign for Democrats, at least six GOP senators have indicated a willingness to oppose the conservatives' efforts to block the gun debate. Sixty votes will be needed to head off the conservative stalling tactics.

"The American people ought to see where everybody stands on this," said Sen. Tom Coburn, R-Okla., who said he wants the debate to proceed.

Also indicating an openness to debate have been GOP Sens. John McCain of Arizona, Lindsey Graham of South Carolina, Susan Collins of Maine, Johnny Isakson of Georgia and Roy Blunt of Missouri.

In a written statement, Sen. Mike Lee, R-Utah, a leader of the effort to block the gun debate, said that effort would prevent Obama from rushing the legislation through Congress "because he knows that as Americans begin to find out what is in the bill, they will oppose it."

The administration was continuing its efforts to pressure Republicans, with Biden and Attorney General Eric Holder making remarks Tuesday at the White House, joined by law enforcement officials.

Democrats were still trying to assess whether Sen. Joe Manchin, D-W.Va., had reached an acceptable compromise ? or had a realistic chance of getting one ? with Sen. Pat Toomey, R-Pa., on expanding background checks for more gun purchases, Obama's pivotal gun control proposal.

Manchin exited a lunch with other Senate Democrats Tuesday and said he would report to Democratic leaders later about the status of his talks with Toomey.

"We're still working," he said, adding, "I've done everything I can."

An agreement between the two senators, both among the more conservative members of their parties, would boost efforts to expand background checks because it could attract bipartisan support. Abandoning those negotiations would put Democrats in a difficult position, making it hard for them to push a measure through the Senate and severely damaging Obama's gun control drive.

Georgia's Isakson said Tuesday on "CBS This Morning" that "the issue on background checks is how far they go and whether they violate rights of privacy." But he also said he believes the issue "deserves a vote up or down" in the Senate.

Manchin has been hoping for a deal with Toomey that would expand the requirement to sales at gun shows and online while exempting other transactions, such as those between relatives and those involving private, face-to-face purchases.

Currently, federal background checks are required for sales by licensed gun dealers but not for other transactions. The system is aimed at preventing criminals, people with severe mental health problems and others from getting firearms.

Sens. Chuck Schumer, D-N.Y., and Mark Kirk, R-Ill., have also continued working for a bipartisan deal. Kirk, though, is considered too moderate to bring other GOP senators with him.

___

Associated Press writers Nedra Pickler, Jim Abrams, Andrew Miga and Henry C. Jackson contributed to this report.

Source: http://news.yahoo.com/top-senate-dem-sets-showdown-gun-vote-thursday-190903216--politics.html

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Monday, April 8, 2013

HTC One for AT&T and Sprint: what's different?

HTC One for AT&T and Sprint: what's different?

You'd think after publishing a 6,000-word review, two hands-on posts and a camera explainer, we would have said all there is to say about the HTC One. Not quite. Though the phone has been available in Germany for about a month now, it's only just arriving in other markets. The US version in particular will see simultaneous launches on AT&T and Sprint, and T-Mobile soon to follow. The AT&T and Sprint variants will be available on April 19th, though you can pre-order either for $200 with a two-year contract. By the by, while all three US carriers will offer a 32GB version, AT&T is also selling a $300 model with 64 gigs of built-in storage -- a useful spec, given that the phone has no microSD slot.

We've just finished taking the AT&T / Sprint models for a spin and, as you'd expect, we like them just as much as the global model. If you're seriously considering getting one, we'd still refer you to our original review for an in-depth take on the design, camera performance and Sense 5 skin. When you're done, though, you might want also to meet us after the break: we've got benchmark scores, network speeds, battery life results and bloatware alerts that apply specifically to those US versions.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/bI27GSJ53nA/

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Pastor Rick Warren says his son committed suicide

LAKE FOREST, Calif. (AP) ? Popular evangelical Pastor Rick Warren asked members of his Southern California church for prayers as he and his family coped with the apparent suicide of his 27-year-old son.

The church said on Saturday that Matthew Warren took his own life at his Mission Viejo home.

Matthew Warren struggled with mental illness, deep depression and suicidal thoughts throughout his life, Saddleback Valley Community Church said in a statement, after his body was found Friday night.

"Despite the best health care available, this was an illness that was never fully controlled and the emotional pain resulted in his decision to take his life," the church said.

Allison O'Neal, a supervising deputy coroner for Orange County, declined to release the cause and manner of death pending an autopsy of the young man.

Rick Warren, the author of the multimillion-selling book "The Purpose Driven Life," said in an email to church staff that he and his wife had enjoyed a fun Friday evening with their son. But their son then returned home to take his life in "a momentary wave of despair."

Over the years, Matthew Warren had been treated by America's best doctors, had received counseling and medication and been the recipient of numerous prayers from others, his father said.

"I'll never forget how, many years ago, after another approach had failed to give relief, Matthew said 'Dad, I know I'm going to heaven. Why can't I just die and end this pain?'" Warren recalled.

Despite that, he said, his son lived for another decade, during which he often reached out to help others.

"You who watched Matthew grow up knew he was an incredibly kind, gentle, and compassionate man," Warren wrote. "He had a brilliant intellect and a gift for sensing who was most in pain or most uncomfortable in a room. He'd then make a bee-line to that person to engage and encourage them."

Another pastor will preach in Warren's place on Sunday as part of a previously planned sermon series, church spokeswoman Kristin Cole said.

The elder Warren founded Saddleback Church in 1980, according to his biography on the church website, and over the years watched it grow to 20,000 members. He and his wife, Kay, began by holding Bible studies for people who weren't regular churchgoers.

Matthew Warren was the youngest of their three children.

As Saddleback grew over the years, it spread out from its Lake Forest headquarters, 65 miles southeast of Los Angeles, adding several other campuses and ministries around Southern California.

The church says it now offers more than 200 community ministries and support groups for parents, families, children, couples, prisoners, addicts, and people living with HIV, depression and other illnesses.

In 2008, the church sponsored a presidential forum with Barack Obama and John McCain. Obama and Republican nominee Mitt Romney were invited to a similar forum last fall, but Warren canceled it several days beforehand, saying the campaign had become too uncivil.

Warren was named the top newsmaker of the year for 2009 by the Religion Newswriters Association. He gained attention that year with his invocation at Obama's inauguration, as well as with comments he made in the aftermath of California's Proposition 8, which overturned gay marriage.

Source: http://news.yahoo.com/pastor-rick-warren-says-son-committed-suicide-080418298.html

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Pfeiffer: Obama won't enact 'Romney economic plan'

Reacting to an early rejection of the expected details of the White House's budget proposal by Speaker John Boehner, President Obama's senior adviser Dan Pfeiffer pushed back this morning on "This Week," saying that the president would not enact "the Romney economic plan."

"What this president will not do is, come in, right after getting re-elected, and enact the Romney economic plan, which is what the Republicans in the House are proposing," Pfeiffer said.

The White House is expected to release details of a budget proposal this week that includes cuts to Social Security and Medicare, which are unpopular among some Democrats.

But Pfeiffer said those entitlement cuts would only happen on two conditions.

"One, it's part of a balanced package that includes asking - closing tax loopholes that benefit the wealthiest, and two, that it has protections for the most vulnerable, including the oldest seniors," he said.

The news of those details in President Obama's budget was met with a swift statement from the House speaker indicating that raising taxes was a non-starter.

abc dan pfeiffer this week jt 130407 wblog Dan Pfeiffer: President Obama Wont Enact Romney Economic PlanPfeiffer on This Week

"When the president visited the Capitol last month, House Republicans stated a desire to find common ground and urged him not to make savings we agree upon conditional on another round of tax increases. If reports are accurate, the president has not heeded that call," Boehner said in a statement Friday. "If the president believes these modest entitlement savings are needed to help shore up these programs, there's no reason they should be held hostage for more tax hikes. That's no way to lead and move the country forward."

Pfeiffer also addressed the ongoing negotiations over a possible bill that would address gun violence in light of the shooting in Newtown, Conn. last year that left 20 children dead. At this point, only a bill that includes new rules on background checks is likely. Pfeiffer scolded Republican members of the Senate for insisting on a filibuster, recalling the president's most recent State of the Union address.

"Every member of Congress stood up and applauded when the president called for an up or down vote on these measures. Now that the cameras are off and they are not forced to look the Newtown families in the face, now they want to make it harder and filibuster it," Pfeiffer said.

Finally, the president's senior adviser addressed tensions between the United States and North Korea. Pfeiffer said the administration would not be surprised if the secretive communist regime conducted another missile test.

"We wouldn't be surprised if they did a test. They've done that in the past. Like I said, this is something that's been going on with North Korea for many, many years, long before President Obama came to power," Pfeiffer said.

Like "This Week" on Facebook here. You can also follow the show on Twitter here.

Go here to find out when "This Week" is on in your area.

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Source: http://news.yahoo.com/dan-pfeiffer-president-obama-wont-145412374.html

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More accurate markers identified for detecting response to epigenetic drugs for myelodysplastic syndromes

Apr. 6, 2013 ? Researchers have identified and validated two DNA methylation markers that could help physicians to more accurately determine a patient's response to epigenetic drugs for treatment of myelodysplastic syndromes (MDS), according to Xiaojing Yang, Ph.D., a postdoctoral fellow at the University of Southern California, Los Angeles, who presented the data at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10.

"The current feedback from physicians is that they cannot tell if a patient is really getting the epigenetic drug they are being treated with or not, which makes it difficult for them to decide whether to stop treatment or increase the dosage of the drug," said Yang. "This pushed us to think, why? Why didn't the current marker work and should we try to seek a better one?"

These drugs, called DNA methyltransferase inhibitors (DNMTi), work by turning on genes that suppress cancer development, according to Yang. In patients with MDS, these genes are often silenced by the attachment of chemicals called methyl groups to the DNA backbone of the gene (an epigenetic modification made through a process called methylation), and DNMTi prevent methyl group attachment to DNA.

Currently, measuring methylation changes in DNA sequences known as LINE-1 elements is widely used as a predictor of whether or not DNMTi are working, but recent research has found that LINE-1 remethylation after a DNMTi is withdrawn occurs faster than in other regions. This implies that LINE-1 methylation changes may not reflect overall demethylation effects of DNMTi, according to Yang.

Yang and colleagues sought to find improved markers of DNA methylation status. Using the Infinium DNA methylation platform, they assessed the methylation profile of 27,000 genomic regions. The team tested this methylation profile on both normal and tumor bladder tissue samples and on white blood cells from healthy donors. They identified 1,429 regions that were consistently methylated in all three samples.

They then tested the methylation profile of these 1,429 regions in T24 bladder cancer and HL60 leukemia cell lines treated with a DNMTi for 24 hours. Of these, 79 significantly responded to demethylation treatment and remained demethylated beyond 30 days. Further analysis focused on the top two regions, which showed consistent hypermethylation in normal and tumor samples.

To verify their findings, Yang and colleagues studied the DNA demethylation levels of those two markers in urine samples from seven patients with MDS treated with the DNMTi azacitidine. They found that the two markers were significantly demethylated, in contrast to LINE-1 methylation, which showed no clear decreasing trend.

According to Yang, these findings could lead to the use of a simple urine test for detecting response to a DNMTi.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/AjrzzyZLaE0/130407090634.htm

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Wednesday, April 3, 2013

Rutgers fires basketball coach Mike Rice after abusive video is broadcast by ESPN

Rutgers University in New Jersey suspended coach Mike Rice after a videotape of him physically and verbally assaulting players on the men's basketball team was presented to university officials last fall. After the tape was broadcast on ESPN Tuesday, the university terminated Rice's employment.

By Tom Canavan,?Associated Press / April 3, 2013

Rutgers coach Mike Rice reacts to play during the first half of an NCAA college basketball game against Georgetown this past February in Piscataway, N.J.

Mel Evans/AP

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Rutgers fired basketball coach Mike Rice on Wednesday after a videotape aired showing him shoving, grabbing and throwing balls at players in practice and using gay slurs during practice.

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The videotape, broadcast Tuesday on ESPN, prompted sharp criticism from Gov. Chris Christie, and the head of the New Jersey Assembly called for Rice to be fired.

With mounting criticism on a state and national level, the school decided to take action, relieving Rice of his duties after three largely unsuccessful seasons at the Big East school. There will be a national search to replace him.

Rutgers athletic director Tim Pernetti was given a copy of the video in late November by a former employee. After hiring independent investigators to analyze the tape, he suspended Rice for three games, fined him $50,000 and ordered him to attend anger management classes. University president Robert Barchi saw the tape and signed off on the initial punishment.

But in a Wednesday email, Rutgers referred to new information and "a review of previously discovered issues" as the reasons for Rice's termination.

"I am responsible for the decision to attempt a rehabilitation of Coach Rice," Pernetti said. "Dismissal and corrective action were debated in December and I thought it was in the best interest of everyone to rehabilitate, but I was wrong. Moving forward, I will work to regain the trust of the Rutgers community."

Rice, who helped Robert Morris to two NCAA tournament appearances, was one of the hot coaching candidates in the spring of 2010. He interviewed with Fordham, where he played as a guard, only to not get the chance to return to his alma mater. Eventually, there was a difference in opinion in the school's search committee, and Rice's fiery, in-game behavior was a sticking point.

But Rutgers, and Pernetti, took a chance on him not long after that. The Scarlet Knights had an opening because of the unexpected dismissal of Fred Hill, Jr., and Rice, who has strong New Jersey recruiting roots, seemed like a fit.

But he wasn't able to push Rutgers into the upper echelon of the conference, and went just 44-51 at Rutgers. Rice posted just a 16-38 mark in the Big East, after going 73-31 in three seasons at Robert Morris. The Scarlet Knights went 15-16 this season and 5-13 in the league.

But his success ? or lack thereof ? on the court is all secondary now. The school is no longer dealing with an issue of wins and losses, but of right and wrong.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/PBfT6WvTZ8k/Rutgers-fires-basketball-coach-Mike-Rice-after-abusive-video-is-broadcast-by-ESPN

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